DM Neonatology Thesis Topics Top 100 Research

Advanced NICU Care & Newborn Medicine 2026

Curated by PubMedico | Call/WhatsApp:
9664299381 |
Visit: www.pubmedico.com

Looking for cutting-edge DM Neonatology research topics?
This comprehensive list by PubMedico includes 100 advanced, high-impact research ideas across all major neonatology subspecialties:
Perinatal Asphyxia & HIE, Neonatal Sepsis & Antimicrobial Resistance, Respiratory Distress & Ventilation Strategies, Prematurity & VLBW Management, Neonatal Nutrition & Growth, Neonatal Neurology, Neonatal Cardiology & Hemodynamics, Quality Improvement in NICU, Emerging Technologies & Point-of-Care Diagnostics, and Family-Centered Developmental Care.
All topics align with latest trends from NIMHANS, AIIMS, JIPMER, PGIMER Chandigarh, and leading neonatal centers worldwide.

Section 1: Perinatal Asphyxia & Hypoxic-Ischemic Encephalopathy

1. Efficacy of Therapeutic Hypothermia in Moderate vs Severe HIE: Long-Term Neurodevelopmental Outcomes
2. Comparative Study of Whole Body vs Selective Head Cooling in Perinatal Asphyxia
3. Amplitude-Integrated EEG as Early Predictor of Neurodevelopmental Outcome in HIE
4. Role of Magnesium Sulfate as Adjunct to Therapeutic Hypothermia in Term Neonates with HIE
5. MRI Brain Findings and Correlation with Bayley-III Scores at 18 Months in HIE Survivors
6. Assessment of Serum Biomarkers (NSE, S100B) in Predicting HIE Severity and Outcomes
7. Early Intervention and Family-Centered Care Impact on Neurobehavioral Outcomes in HIE
8. Comparative Analysis of Cooling Duration: 72 Hours vs Extended Protocol in Severe HIE
9. Study on Fluid Restriction vs Standard Fluid Management During Therapeutic Hypothermia
10. Evaluation of Cerebral Oxygenation Using NIRS During Rewarming Phase in HIE

Section 2: Neonatal Sepsis & Antimicrobial Resistance

1. Clinical Profile and Antimicrobial Resistance Patterns in Early vs Late-Onset Neonatal Sepsis
2. Efficacy of Probiotic Supplementation in Prevention of Sepsis in VLBW Infants: RCT
3. Role of Procalcitonin vs CRP in Early Diagnosis of Neonatal Sepsis
4. Epigenetic Regulation of Host Immune Response in Neonatal Sepsis: Molecular Study
5. Burden of Multidrug-Resistant Gram-Negative Sepsis in Level III NICU
6. Comparative Study of Antibiotic Stewardship Programs in Reducing Sepsis Mortality
7. Assessment of Whole Blood Transcriptomics in Differentiating Bacterial vs Viral Sepsis
8. Role of Fungal Prophylaxis in Extremely Low Birth Weight Infants
9. Evaluation of Point-of-Care Molecular Diagnostics in Rapid Sepsis Detection
10. Study on Coagulase-Negative Staphylococcus: Pathogen vs Contaminant in Blood Cultures

Section 3: Respiratory Distress Syndrome & Ventilation Strategies

1. Comparison of Porcine vs Bovine Surfactant in Preterm Neonates with RDS
2. Efficacy of Less Invasive Surfactant Administration (LISA) vs INSURE Technique
3. Evaluation of Volume-Targeted vs Pressure-Controlled Ventilation in ELBW Infants
4. Role of High-Flow Nasal Cannula vs CPAP as Primary Respiratory Support
5. Assessment of Neurally Adjusted Ventilatory Assist (NAVA) in Neonatal Ventilation
6. Cerebral Oxygenation Monitoring During Surfactant Replacement Therapy Using NIRS
7. Study on Optimal PEEP Strategy in Preventing BPD in Extremely Preterm Infants
8. Comparative Analysis of Early vs Delayed Extubation and BPD Outcomes
9. Evaluation of Non-Invasive Neurally Adjusted Ventilatory Assist (NIV-NAVA)
10. Role of Caffeine Citrate in Reducing Mechanical Ventilation Duration

Section 4: Prematurity & Very Low Birth Weight Management

1. Predictors of Mortality and Major Morbidities in Extremely Low Birth Weight Neonates
2. Incidence and Risk Factors of Intraventricular Hemorrhage in VLBW Infants
3. Comparative Study of Kangaroo Mother Care Duration: Intermittent vs Continuous
4. Quality Improvement Initiative to Reduce Postnatal Growth Failure in VLBW Babies
5. Assessment of Retinopathy of Prematurity: Screening Protocols and Laser Therapy Outcomes
6. Neurodevelopmental Outcomes of Preterm IUGR Neonates at 2 Years: Cohort Study
7. Role of Delayed Cord Clamping vs Cord Milking in Preterm Neonates
8. Evaluation of Late-Onset Circulatory Collapse in ELBW Infants
9. Study on Optimal Oxygen Saturation Targets in Preventing ROP and BPD
10. Assessment of Neonatal Pain Using Validated Scales During NICU Procedures

Section 5: Neonatal Nutrition & Growth

1. Impact of Human Milk Bank on Mortality and Morbidity Patterns in NICU
2. Stratified Pooling of Donor Human Milk for Improving Nutritional Quality: Study
3. Efficacy of Oropharyngeal Colostrum Administration in VLBW Infants: RCT
4. Comparative Study of Early vs Late Introduction of Trophic Feeds in ELBW
5. Role of Human Milk Fortification in Growth Velocity of Preterm Infants
6. Assessment of Postnatal Growth Restriction and Neurodevelopmental Outcomes
7. Study on Optimal Protein Intake in Extremely Preterm Infants
8. Evaluation of Parenteral Nutrition-Associated Liver Disease in VLBW Infants
9. Role of Probiotics in Preventing Necrotizing Enterocolitis: Meta-Analysis
10. Assessment of Micronutrient Deficiencies in Preterm Infants at Discharge

Section 6: Neonatal Neurology & Developmental Care

1. Neurodevelopmental Outcomes of High-Risk Neonates Using Bayley-III at 18-24 Months
2. Comparative Analysis of General Movements Assessment in Predicting Cerebral Palsy
3. Role of Early Physiotherapy and Family-Centered Intervention in NICU Graduates
4. Assessment of Neonatal Seizures: Correlation Between Clinical, EEG, and MRI Findings
5. Evaluation of Developmental Care Practices on Neurobehavioral Outcomes
6. Study on Impact of NICU Noise and Light Levels on Sleep-Wake Cycles
7. Long-Term Outcomes of Neonatal Stroke: Neuroimaging and Follow-Up Study
8. Role of Music Therapy in Neurodevelopment of Preterm Infants
9. Assessment of Hearing Screening Using OAE and BERA in NICU Graduates
10. Evaluation of Congenital Infections (TORCH) and Neurological Sequelae

Section 7: Neonatal Cardiology & Hemodynamic Monitoring

1. Functional Echocardiography in Assessing Hemodynamic Significance of PDA
2. Comparative Study of Paracetamol vs Ibuprofen in Prophylactic PDA Closure
3. Role of Targeted Neonatal Echocardiography in Optimizing Cardiovascular Support
4. Assessment of Persistent Pulmonary Hypertension: Echo and Blood Gas Correlation
5. Study on Optimal Timing of PDA Intervention in ELBW Infants
6. Evaluation of Tissue Doppler Imaging in Neonatal Myocardial Function
7. Role of Near-Infrared Spectroscopy in Monitoring Cerebral Perfusion
8. Comparative Analysis of Dopamine vs Dobutamine in Neonatal Hypotension
9. Assessment of Superior Vena Cava Flow as Marker of Systemic Blood Flow
10. Study on Cardiac Troponins as Biomarkers in Perinatal Asphyxia

Section 8: Neonatal Quality Improvement & Patient Safety

1. Implementation of Bundle Approach in Reducing Central Line-Associated Bloodstream Infections
2. Quality Improvement Project: Reducing Medication Errors in NICU Using FMEA
3. Assessment of Hand Hygiene Compliance and Healthcare-Associated Infections
4. Study on Golden Hour Protocol Implementation and Admission Hypothermia Rates
5. Evaluation of Standardized Feeding Protocol in Reducing NEC Incidence
6. Role of Daily Multidisciplinary Rounds in Reducing Length of NICU Stay
7. Assessment of Skin-to-Skin Contact Duration and Breastfeeding Outcomes
8. Quality Metrics in NICU: Vermont Oxford Network Data Analysis
9. Study on Reducing Unplanned Extubations Through Nurse-Driven Protocols
10. Evaluation of Discharge Readiness Assessment Tools in NICU

Section 9: Emerging Technologies & Point-of-Care Diagnostics

1. Role of Artificial Intelligence in Predicting Sepsis Using Vital Sign Analysis
2. Evaluation of Telemedicine in Neonatal Follow-Up During Pandemic: RCT
3. Assessment of Wearable Sensors for Continuous Physiological Monitoring
4. Study on Point-of-Care Ultrasound in NICU: Diagnostic Accuracy and Training
5. Role of Rapid Molecular Testing in Reducing Antibiotic Exposure
6. Evaluation of Transcutaneous Bilirubin Measurement vs Serum Bilirubin
7. Assessment of Video EEG Monitoring in Neonatal Seizure Detection
8. Study on Automated Oxygen Control Systems in Reducing Hypoxemia Episodes
9. Role of Digital Health Records in Improving NICU Workflow Efficiency
10. Evaluation of Non-Contact Vital Sign Monitoring Using Camera-Based Systems

Section 10: Family-Centered Care & Parental Support

1. Impact of Parental Presence During Rounds on NICU Outcomes and Satisfaction
2. Assessment of Maternal Mental Health (Depression, Anxiety) in NICU Parents
3. Evaluation of Structured Discharge Education on Post-Discharge Readmission Rates
4. Role of Peer-to-Peer Support Groups in Parental Coping and Bonding
5. Study on Impact of Single-Family Room NICU Design on Developmental Outcomes
6. Assessment of Father Involvement in NICU Care and Paternal Bonding
7. Evaluation of Video Recording for Remote Family Connection in Pandemic
8. Role of Bedside Nurse Education on Breastfeeding Success Rates
9. Study on Post-Discharge Follow-Up Using Mobile Health Apps
10. Assessment of Parental Satisfaction with NICU Care Using Validated Tools

📚 Explore More:
MD Pediatrics Thesis Topics |
DM Cardiology Topics |
General Medicine PG Topics